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1. Melo RC., Liu L., Xenakis JJ., Spencer LA. Eosinophil-derived cytokines in health and disease: unraveling novel mechanisms of selective secretion.  Allergy. 2013:68:274-94.

2. Fung-Leung WP, De Sousa-Hitzler J, Ishaque A,  et al. Transgenic mice expressing the human high-affinity immunoglobulin (Ig) E receptor alpha chain respond to human IgE in mast cell degranulation and in allergic reactions. J Exp Med. 1996; 183:49-56.

3. Uzzaman A, Cho SH. Chapter 28: Classification of hypersensitivity reactions.Allergy Asthma Proc. 2012;33 Suppl 1:S96-9.

4. Uzunismail H., Hatemi I., Doğusoy G, Akin O.:  Dense eosinophilic infiltration of the mucosa preceding ulcerative colitis and mimicking eosinophilic colitis: report of two cases. Turk J Gastroenterol.  2006;17:53-7.

5. O’Sullivan M, Clayton N, Breslin NP, et al. Increased mast cells in the irritable bowel syndrome. Neurogastroenterol Motil. 2000;12:449-57.

6. Sohn W, Lee OY, Lee SP, et al. Scand J Gastroenterol. 2014;49:43-51. Mast cell number, substance P and vasoactive intestinal peptide in irritable bowel syndrome with diarrhea.

7. Theoharides TC, Alysandratos KD, Angelidou A, et al. Mast cells and inflammation. Biochim Biophys Acta. 2012;1822:21-33.

8. Theoharides TC, Kalogeromitros D. The critical role of mast cells in allergy and inflammation. Ann N Y Acad Sci. 2006;1088:78-99.

9. Alevizos M, Karagkouni A, Panagiotidou S et al. Stress triggers coronary mast cells leading to cardiac events. Ann Allergy Asthma Immunol. 2014;112:309-16.

10. He SH, Zhang HY, Zeng XN, Chen D, Yang PC. Mast Cells and basophils are essential for allergies: mechanisms of allergic inflammation and aproposed procedure for diagnosis. Acta Pharmacol Sin. 2013;34:1270-83.

11. Malbec O., Daëron M. The mast cell IgG receptors and their roles in tissue inflammation. Immunol Rev. 2007;217:206-21.

12. Walker ME, Hatfield JK, Brown MA. New insights into the role of mast cells in autoimmunity: evidence for a common mechanism of action? Biochim Biophys Acta. 2012; 1822:57-65.

13. Jönsson F., Daëron M. Mast cells and company. Front Immunol. 2012 20;3:16.

14. He S, Zhang H, Zeng X, Yang P. Self-amplification mechanisms of mast cell activation: a new look in allergy. Curr Mol Med. 2012;12:1329-39.

15. Lee H, Kashiwakura J, Matsuda A, Watanabe Y, Sakamoto-Sasaki T, et al. Activation of human synovial mast cells from rheumatoid arthritis or osteoarthritis patients in response to aggregated IgG through Fcγ receptor I and Fcγ receptor II. Arthritis Rheum. 2013; 65:109-19.16.

16. Ghably J, Saleh H, Vyas H, et al.Paul Ehrlich’s mastzellen: a historical perspective of relevant developments in mast cell biology. Methods Mol Biol. 2015;1220:3-10.

17. Narita S, Goldblum RM, Watson CS, et al. Environmental estrogens induce mast cell degranulation and enhance IgE-mediated release of allergic mediators. Environ Health Perspect. 2007;115:48-52.

18. Barbaud A. Physical urticarias Ann Dermatol Venereol. 2003;130 Spec No 1:1S16-27.

19. Pettigrew HD, Teuber SS, Kong JS, Gershwin ME. Contemporary challenges in mastocytosis. Clin Rev Allergy Immunol. 2010 ;38:125-34. 20. Zierau O, Zenclussen AC, Jensen F. Role of female sex hormones,

18. Barbaud A. Physical urticarias Ann Dermatol Venereol. 2003;130 Spec No 1:1S16-27.  19. Pettigrew HD, Teuber SS, Kong JS, Gershwin ME. Contemporary challenges in mastocytosis. Clin Rev Allergy Immunol. 2010 ;38:125-34.

19. Pettigrew HD, Teuber SS, Kong JS, Gershwin ME. Contemporary challenges in mastocytosis. Clin Rev Allergy Immunol. 2010 ;38:125-34.

20. Zierau O, Zenclussen AC, Jensen F. Role of female sex hormones, estradiol and progesterone, in mast cell behavior. Front Immunol. 2012 ,3:169.  

21. Bonds RS, Midoro-Horiuti T. Estrogen effects in allergy and asthma. Estrogen effects in allergy and asthma. Curr Opin Allergy Clin Immunol. 2013 ;13:92-9.

22. Hügle T.Beyond allergy: the role of mast cells in fibrosis. Swiss Med Wkly. 2014;144:w13999

23. Xu Y, Chen G. Mast cell and autoimmune diseases. Mediators Inflamm. 2015;2015:246126.

24. Brown MA, Hatfield JK. Mast Cells are Important Modifiers of Autoimmune Disease: With so Much Evidence, Why is There Still Controversy? Front Immunol. 2012;3:147.

25. Theoharides TC, Asadi S, Panagiotidou S, Weng Z. The “missing link” in autoimmunity and autism: extracellular mitochondrial components secreted from activated live mast cells.  Autoimmun Rev. 2013 ;12:1136-42.

26. Spinas E, Kritas SK, Saggini A, et al. Role of mast cells in atherosclerosis: a classical inflammatory disease. Int J Immunopathol Pharmacol. 2014;27:517-21.

27. Bot I, Shi GP, Kovanen PT. Mast cells as effectors in atherosclerosis. Arterioscler Thromb Vasc Biol. 2015;35:265-71.

28. Skaper SD, Facci L, Giusti P. Mast cells, glia and neuroinflammation: partners in crime? Immunology. 2014; 141:314-27.

29. Maciel TT., Moura IC., Hermine O. The role of mast cells in cancers. F1000 Prime Rep. 2015;7:09.

30. Manzotti G, Breda D, Di Gioacchino M, Burastero SE. Serum diamine oxidase activity in patients with histamine intolerance. Int J Immunopathol Pharmacol. 2015 Nov 16.

31. Azuma K, Uchiyama I, Katoh T, et al.Prevalence and Characteristics of Chemical Intolerance: A Japanese Population-Based Study. Arch Environ Occup Health. 2015 ;70:341-53.

32. Abraham SN, St John AL. Mast cell-orchestrated immunity to pathogens. Nat Rev Immunol. 2010;10:440-52.

33. Guhl S, Artuc M, Zuberbier T, Babina M. Testosterone exerts selective anti-inflammatory effects on human skin mast cells in a cell subset dependent manner.Exp Dermatol. 2012 ;21:878-80.

34. King TS, Woolner JT, Hunter JO. Review article: the dietary management of Crohn’s disease. Aliment Pharmacol Ther. 1997;11:17-31.

35. Fälström SP, Ahlstedt S, Hanson LA. Specific antibodies in infants with gastrointestinal intolerance to cow’s milk protein. Int Arch Allergy Appl Immunol. 1978;56(2):97-105.

36. Fällström SP, Ahlstedt S, Carlsson B, Lönnerdal B, Hanson LA. Serum antibodies against native, processed and digested cow’s milk proteins in children withcow’s milk protein intolerance. Clin Allergy. 1986;16:417-23.

37. Shakib F, Brown HM, Phelps A, Redhead R. Study of IgG sub-class antibodies in patients with milk intolerance. Clin Allergy. 1986 ;16:451-8.

38. Taylor CJ, Hendrickse RG, McGaw J. Macfarlane SB. Detection of cow’s milk protein intolerance by an enzyme-linked immunosorbent assay. Acta Paediatr Scand. 1988;77(1):49-54.

39. Saalman R, Fällström SP, Carlsson B,  Hanson LA.  Antibody-dependent cell-mediated cytotoxicity to beta-lactoglobulin-coated cells with sera from children with intolerance of cow’s milk protein. Ahlstedt S. Clin Exp Immunol. 1991 ;85:446-52.

40. Iacono G, Carroccio A, Cavataio F, et al. IgG anti-betalactoglobulin (betalactotest): its usefulness in the diagnosis of cow’s milk allergy. Ital J Gastroenterol. 1995;27:355-60.

41. Little CH, Georgiou GM, Shelton MJ, Cone RE.  Production of serum immunoglobulins and T cell antigen binding molecules specific for cow’smilk antigens in adults intolerant to cow’s milk. Clin Immunol Immunopathol. 1998 ;89:160-70.

42. Kokkonen J, Tikkanen S, Karttunen TJ, Savilahti E. A similar high level of immunoglobulin A and immunoglobulin G class milk antibodies and increment of local lymphoid tissue on the duodenal mucosa in subjects with cow’s milk allergyand recurrent abdominal pains. Pediatr Allergy Immunol. 2002 ;13:129-36.

43. Keller KM, Bürgin-Wolff A, Lippold R, Wirth S, Lentze MJ.  The diagnostic significance of IgG cow’s milk protein antibodies re-evaluated. Eur J Pediatr. 1996 ;155:331-7.

44. Ahmed T, Sumazaki R,  Nagai Y, Shibasaki M, Takita H.  Immune response to food antigens: kinetics of food-specific antibodies in the normal population. Acta Paediatr Jpn. 1997 ;39:322-8. 45.

45. Keller KM, Bürgin-Wolff A, Lippold R, Lentze MJ. Quality assurance in diagnostics: are there normal values for IgG-antibodies to cow’s milk proteins?. Klin Padiatr. 1999;211:384-8.

46. Husby S, Oxelius VA, Teisner B, Jensenius JC, Svehag SE. Humoral immunity to dietary antigens in healthy adults. Occurrence, isotype and IgG subclass distribution of serum antibodies to protein antigens. Int Arch Allergy Appl Im munol. 1985; 77:416-22.

47. Dixon HS.Treatment of delayed food allergy based on specific immunoglobulin  G RAST testing.Otolaryngol Head Neck Surg. 2000;123:48-54.

48. Atkinson W, Sheldon TA, Shaath N, Whorwell PJ. Food elimination based on IgG antibodies in irritable bowel syndrome: a randomized controlled trial. Gut. 2004;53:1459–1464.

49. Zar S, Mincher L, Benson MJ, Kumar D. Food-specific IgG4 antibody-guided exclusion diet improves symptoms and rectal compliance in irritable bowel syndrome. Scand J Gastroenterol. 2005 ;40:800-7.

50. Alpay K, Ertas M, Orhan EK, Ustay DK, Lieners C, et al. (2010) Diet restriction in migraine, based on IgG against foods: a clinical double-blind, randomised, cross-over trial. Cephalalgia. 2010;30:829-37.

51. Yang CM, Li YQ. The therapeutic effects of elimination allergic foods according to food-specific IgG antibodies in irritable bowel syndrome. Zhonghua Nei Ke Za Zhi. 2007; 46:641-3.

52. Guo H, Jiang T, Wang J, Chang Y, Guo H, Zhang W. The value of eliminating foods according to food specific immunoglobulin G antibodies in irritable bowel syndrome with diarrhea. J Int Med Res. 2012;40:204-10.

53. Aydinlar EI, Dikmen PY, Tiftikci A, Saruc M, Aksu M, et al. IgG-based elimination diet in migraine plus irritable bowel syndrome. Headache. 2013;53:514-25.

54. Calderon TE, Ferrero M, Marino GM,et al. Meat-specific IgG and IgA antibodies coexist with IgE antibodies in sera from allergic patients: clinical association and modulation by exclusion diet. J Biol Regul Homeost Agents. 2010;24:261-71.

55. Moissidis I1, Chaidaroon D, Vichyanond P, Bahna SL. Milk-induced pulmonary disease in infants (Heiner syndrome).Pediatr Allergy Immunol. 2005;16:545-52.

56. Feltelius N, Hällgren R, Venge P. Raised circulating levels of the eosinophil cationic protein in ankylosing spondylitis: relation with the inflammatory activity and the influence of sulphasalazine treatment. Ann Rheum Dis. 1987 May;46(5):403-7.

57. Bentz S, Hausmann M, Piberer H. Et al. Clinical relevance of IgG antibodies against food antigens in Crohn’s disese. A doble-blind cross-over diet intervention study. Digestion, 2010; 81:252-64

58. Rajendran N, Kumar D.Food-specific IgG4-guided exclusion diets improve symptoms in Crohn’s disease: a pilot study. Colorectal Dis. 2011;13:1009-13.

59. Uzunismail H, Cengız M, Uzun H, Ozbakir F. et al. The effects of provocation by foods with raised IgG antibodies and additives on the course of Crohn’s disease. Turk J Gastroenterol. 2012 ;23:19-27.

60. de Magistris L, Picardi A, Siniscalco D, et al. Antibodies against food antigens in patients with autistic spectrum disorders. Biomed Res Int. 2013;2013:729349.

61. Volta U, Tovoli F, Cicola R, et al. Serological tests in gluten sensitivity (nonceliac gluten intolerance).J Clin Gastroenterol. 2012;46:680-5.

62. Barclay GR, McKenzie H, Pennington J, Parratt D, Pennington CR. The effect of dietary yeast on the activity of stable chronic Crohn’s disease. Scand J Gastroenterol. 1992;27:196-200.

63.lucarelli S, Frediani T, Zingoni AM, Ferruzzi F, Giardini O, et al. Food allergy and infantile autism. Panminerva Med. 1995; 37:137-41.

64. Michaëlsson G, Gerdén B, Hagforsen E, Psoriasis patients with antibodies to gliadin can be improved by a gluten-free diet. Br J Dermatol. 2000 Jan;142(1):44-51.

65. Lucarelli S, Quattrucci S, Zingoni AM, Frediani T, Diamanti S,et al. Food allergy in cystic fibrosis.  Minerva Pediatr. 1994; 46:543-8.

66. Ou-Yang WX, You JY, Duan BP, Chen CB Application of food allergens specific IgG antibody detection in chronic diarrhea in children. Zhongguo Dang Dai Er Ke Za Zhi. 2008; 10:21-4.

67. Arroyave Hernández CM, Echavarría Pinto M, Hernández Montiel HL.Food allergy mediated by IgG antibodies associated with migraine in adults. Rev Alerg Mex. 2007;54:162-8.

68. Mitchell N, Hewitt CE, Jayakody S, Islam M, Adamson J, et al. Randomised controlled trial of food elimination diet based on IgG antibodies for the prevention of migraine like headaches. 2011, Nutr J 10:85.

69. Pelsser LM, Frankena K, Toorman J, Savelkoul HF, Dubois AE, et al. Effects of a restricted elimination diet on the behaviour of children with attention-deficithyperactivity disorder (INCA study): a randomised controlled trial. Lancet. 2011;377(9764):494-503.

70. Hon KL, Poon TC, Pong NH, Wong YH, Leung SS, et al. Specific IgG and IgA of common foods in Chinese children with eczema: friend or foe. J Dermatolog Treat. 2014;25:462-6

71. Virdee K, Musset J, Baral M, Cronin C, Langland J. Food-specific IgG Antibody-guided Elimination Diets Followed by Resolution of Asthma Symptoms and Reduction in Pharmacological Interventions in Two Patients: A Case Report. Glob Adv Health Med. 2015;4:62-6.

72. Zeng Q, Dong SY, Wu LX, Li H, Sun ZJ, et al. Variable food-specific IgG antibody levels in healthy and symptomatic Chinese adults.  PLoS One. 2013;8:e53612.

73. Ligaarden SC, Lydersen S, Farup PG. IgG and IgG4 antibodies in subjects with irritable bowel syndrome: a case control study in the general population. BMC Gastroenterol. 2012;12:166.

74. Cai C, Shen J, Zhao D, Qiao Y, Xu A, et al. Serological investigation of food specific immunoglobulin g antibodies in patients with inflammatory bowel diseases. PLoS One. 2014; 9(11):e112154.

75. Vidarsson G, Dekkers G, Rispens T. IgG subclasses and allotypes: from structure to effector functions. Front Immunol. 2014, 20;5:520.

76. Stapel SO, Asero R, Ballmer-Weber BK, et al. Testing for IgG4 against foods is not recommended as a diagnostic tool: EAACI Task Force Report. Allergy. 2008;63:793-6.

77. Hong GU, Lim JY, Kim NG, Shin JH, Ro JY. IgE and IgA produced by OX40-OX40L or CD40-CD40L interaction in B cells-mast cells re-activate FcεRI or FcαRI on mast cells in mouse allergic asthma. Eur J Pharmacol. 2015;754:199-210.

78. Boyce JA, Assa’ad A, Burks AW, et al. Guidelines for the diagnosis and management of food allergy in the United States: summary of the NIAID-sponsored expert panel report. J Allergy Clin Immunol. 2010;126(6):1105-18.

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43 yıl aktif olarak çalışmış, bunun yaklaşık son 25 yılını da, gıda-hastalık ilişkisini bulma uğraşına adamış bir iç hastalıkları ve gastroenteroloji uzmanı olarak derlediğim bilgi ve deneyimlerimi, hem doktorlar hem de hastalar için bir kitapta birleştirerek paylaşmak istedim.