Gluten can also cause mental blurriness!

zihin bulanikligi - brain fog
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One of the common complaints about non-celiac gluten sensitivity that has been raised in recent years is the blur of the mind. With these words, it is desirable to describe situations of difficulty in understanding what is said, responding to questions, remembering, gathering attention, decreased clarity of mind and confusion. In fact, it is not considered a symptom of a disease, even by family members, since those counted are not observed very rarely. However, due to the increased Alzheimer's disease in recent years, people over the age of sixty are given separate care and immediately consult neurologists.

Mental blurring is a frequent complaint that internal medicine specialists and gastroenterologists also encounter

Although the blur of the mind is perceived as a complaint concerning neurologists and psychiatrists, gastroenterologists or internal medicine specialists are often encountered. Often accompanied by abdominal pain, bloating, diarrhea, constipation and stomach pain, as well as general malaise or feeling of malaise in the digestive system, muscle-joint pain, numbness of the hands and feet, headache There are complaints. After explaining these main complaints, patients end their words by saying, “I can't get my head together.” As the cause of mental turbidity, anemia, iron, folic acid and vitamin B12, D deficiency is considered and necessary treatment is performed if it is detected in routine tests. Increase blood flow in the brain for many years, depending on the patient's condition, due to old age, excessive stress, insomnia or excessive fatigue in the body or head, even when these values are within normal limits In order to start treatment by writing the famous drug used. But those who have very pronounced complaints or do not take advantage of the treatment administered are referred to neurologists.

Causes of mind blur

The Entrez pubmed site, which has recovered the scientific medical publications, provides only non-celiac gluten sensitivity as the cause of mind blur. But on other sites on the Internet, besides what I write, there are different and logical reasons. For example, low-fat dietary nutrition, dehydration, inflammation of the brain, food allergy are among them. In addition, food additives such as MSG (monosodium glutamate) and the effects of sweeteners such as aspartame should not be ignored (1).


What are the gluten-related diseases?

Gluten is the common name given to gluten and gliadine, two of the four wheat proteins. In 2011, non-celiac gluten susceptibility was added to the two diseases (celiac disease and wheat allergy) that have been known to be caused by the harmful effect of gluten for many years. In this disease, there are often complaints of abdominal pain, bloating, diarrhea, constipation, excessive flatulence, stomach pain and burning, mouth abscesses of the digestive tract. Also, weakness, inability to feel well, blurred mind, headache, numbness of hands and feet, muscle and joint pains similar to fibromyalgia, muscle cramps, depression, irritability, cerebellar atax, general, neurological and psychiatric complaints and diseases such as learning difficulties, autism, vision and hearing hallucinations, schizophrenia can be found either alone or with complaints of the digestive system (2-4) (see, Book, p.89-100).

Although non-celiac gluten sensitivity is recognized by gastroenterologists so late, the harmful effect of gluten has been considered by some neurologists and psychiatry doctors for many years. It was called gluten sensitivity. In fact, that's the right name and I think in a short time only the name of gluten sensitivity will be considered, even if it has already begun to be used (4). The frequency of the disease is currently calculated at 3 -6%, but it needs to be much higher. Because abdominal pain, swelling and diarrhea of the digestive tract are also the main complaints of irritable bowel syndrome, the frequency of which reaches 20%, and the likelihood of mixing of the two diseases is high.

How to diagnose non-celiac gluten sensitivity?

The peculiarity of this disease is that counted complaints pass through gluten-free diet (see, Book, p.91-95) and also occurs with ingestion of gluten-containing foods. Of course, gluten is observed in complaints related to the digestive system, but also for complaints such as mental blurring, weakness, feeling of malaise, musculoskeletal pain, numbness of hand and foot. applies.

It is difficult to diagnose a disease only by what the patient feels. Together, at least one laboratory evidence should be found. Thus, both the diagnosis is supported and the gluten-free diet is more reliable. There is a test used for many years in the diagnosis of celiac disease, but later abandoned by many laboratories because it is not very sensitive and more sensitive tests came up (see, Book, p.89). This test shows the amount of IgA and IgG antibodies to gliadine (IgA and IgG AGA). What is confusing is that in recent years it is valuable for celiac disease, but different from the known AGA, a test given similar name (anti-deamide gliadin peptide or anti-dgliadin antibody) has been raised is the arrival. This final test is performed both in private laboratories and in some state hospitals instead of AGA. However, in a study conducted in the first years of non-celiac gluten sensitivity, IgG AGA was found to be 56.4% and IgA AGA increased by 7% (positive) in these patients (6). In this case, at least in 64% of patients, a laboratory test also supports the diagnosis. This result is not achieved with the new test instead of AGA tests.



Every complaint about gluten sensitivity is important, but mind blur is a difficult condition that disturbs people. If together there is a feeling of numbness in the feet, excessive weakness and malaise in the hands, the patient begins to circulate the doctor to the doctor. But what saddens them most is that despite the studies conducted, there is no reason and they are treated as a hypochondriac. Then the possibility of non-celiac gluten sensitivity in these patients should definitely come to mind. Furthermore, other causes should be investigated in cases of mental turbidity that cannot be achieved by gluten-free diet. It should also be noted that food allergies and non-gluten food sensitivities, especially.

Book: Now I Can Cope With My Disease (The Myth of Mast Cells), Nobel Medical Bookstores.



2.Losurdo G, Principi M, Iannone A, take meat. Extra-intestinal manifestations of non-celiac gluten sensitivity: An expanding paradigm.World J Gastroenterol. 2018; 24:1521 -1530.

Volta U, Bardella MT, Calabrò A, et al. An Italian prospective multicenter survey on patients suspected of having non-celiac glutensensitivity. BMC Med. 2014; 12:85.

Catassi C. Gluten Sensitivity. Ann Nutr Metab. 2015; 67 Suppl 2:16 -26.

Catassi C, Alaedini A, Bojarski C, take the meat. The Overlapping Area of Non-Celiac Gluten Sensitivity (NCGS) and Wheat-Sensitive Irritable Bowel Syndrome (IBS): An Update. Nutrients. 2017 Nov 21; 9 (11). pii: E1268.

Volta U, Tovoli F, Cicola R, et al. Serological tests in gluten sensitivity (nonceliac gluten intolerance) .J Clin Gastroenterol. 2012; 46:680 -5.

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